Disability charity Scope said 53% of disabled people have been bullied or harassed in the workplace because of their impairments.
Its poll of 500 disabled people from across the UK found that one in five (21%) try to hide their disability from their employers.
Thirteen per cent said they have been overlooked for a promotion and a quarter said their employer is not supportive of their disability.
Meanwhile, over half (58%) said they felt at risk of losing their job due to their disability.
Scope Chief Executive Mark Atkinson said: “These figures demonstrate that employers and Government need to be doing much more to support disabled people in the workplace.”