Police have seized more than £300,000 worth of drugs, searched more than 1,000 properties and arrested 309 people in Northern Ireland the past two weeks.
The clampdown, known as Operation Torus, is part of a major effort to deal with street-level drug dealing.
The initiative, which will also feature a media campaign and advertising, has been re-launched to raise awareness of drugs and encourage the public to give police information in a bid to rid the streets of dealers.
Between October last year and last month the PSNI seized almost £10m worth of drugs, arresting almost 3,000 people for drug offences.
Seizures to date include cocaine, cannabis, mephedrone and prescription drugs.
The media campaign, across billboards, Facebook and advertising in restrooms, will run for the next two weeks.
Superintendent Michele Larmour said help from the public is essential in the fight against drugs.
“We know that street-level drug dealing is happening across all Districts throughout Northern Ireland, but we need the help and support of local communities to remove this activity from our streets. If you know or suspect that illegal drugs are being sold or distributed in your area, please pick up the phone and contact your local Neighbourhood Policing Team on 0845 600 8000.”
Superintendent Larmour warned of the fallout from drug addiction.
“Drugs bring misery to individuals, families and communities. I want to warn people to be mindful of the dangers of taking illegal drugs or misusing prescription medication or other chemical products,” she said.
“Parents need to be responsible, knowing where their children are and what they are doing. Young people who take illegal drugs may get into dangerous situations or activities that they would not normally dream of doing.
“It may also lead to a criminal record which can damage employment and travel prospects. In addition, this type of behaviour has the potential to seriously affect the quality of life for many residents in a community.
“We will continue to disrupt and arrest drug dealers involved in the sale and supply of drugs, bring individuals before the courts and work with communities and partner agencies to reduce the threat of harmful and illegal activity.
“We are asking everyone for their support and co-operation in tackling this problem through the criminal justice system.
“Our message today is clear and simple: if you see or know of anyone who is dealing drugs in your local area, then contact your local police on 0845 600 8000 or alternatively you can contact the independent charity Crimestoppers anonymously on 0800 555 111 and pass on any details that you may have.
“This is about empowering and working with local communities to make their neighbourhoods safer, reducing the threat posed by street-level drugs and dealing with offenders robustly through the criminal justice system.