NCU Premier League new boys Muckamore have been handed a daunting trip to holders Merrion in the second round of this year’s competition.
The Moylena side, who defeated Ardmore in the first round on Saturday, will make the trip to Dublin on Sunday, June 11.
All other five Leinster sides are on the road, with two-time winners The Hills facing a tough tie at 2000 winners Donemana.
Phoenix, winners in 1986 are at three times champions North Down, while YMCA take on CIYMS, conquerors of five times winners North County.
Balbriggan, who beat Drummond in their first tie in the competition on Saturday, are away at Lisburn.
Bready, beaten finalists in 1995, have home advantage over Pembroke, while also in the North-West, Coleraine entertain four times winners Waringstown, who have appeared in the final in the last two years.
The final tie is also an intriguing one with NCU league champions Instonians, the runners-up in 2011 hosting two times champions Brigade.
In the National Cup, winners in the past two seasons Rush have been handed a home tie against Killyclooney, who were runners-up in 2014.
Derriaghy, finalists in 2013 are home to Sion Mills, while also in the NCU region, Cregagh host Strabane.
The winners of the Bonds Glen v North Kildare replay face the long trip to County Kerry, while Burndennett are also on their travels away at Munster side Midleton.
Terenure host Limerick, Malahide entertain Downpatrick, while Newbuildings have home advantage over Knockharley.
The matches in both competitions will be played on Sunday June 11th, with the reserve date, if required, Sunday June 18.
IRISH SENIOR CUP DRAW
Lisburn v Balbriggan
CIYMS v YMCA
North Down v Phoenix
Donemana v The Hills
Coleraine v Waringstown
Bready v Pembroke
Instonians v Brigade
Merrion v Muckamore
IRISH NATIONAL CUP DRAW
Midleton v Burndennett
Newbuildings v Knockharley
Malahide v Downpatrick
Derriaghy v Sion Mills
County Kerry v Bonds Glen/North Kildare
Rush v Killyclooney
Cregagh v Strabane
Terenure v Limerick