Ballynahinch can take a step closer to promotion as they travel to relegation threaten Bruff.
The Ballymacarn side are eight points clear of second placed UCD in the race for the one automatic promotion place to Division 1A.
Hinch are 34 points ahead of their opponents from Limerick but Bruff ran Belfast Harlequins close last week.
Roger McBurney returns at full for Hinch, with Michael Lawton and Aaron Ferris on the wings, Stuart Morrow are James Thompson are in midfield with Blane McIlroy and Harry McAleese at half back.
The pack is the same as the one that started the 66-5 win over Ballymena last Saturday.
Chris Stevenson captains the side from loose head prop, Kyle McCall is at tight head and Gavin Armstrong hooks.
James Simpson and Chris Napier are in the second row, with Niel Faloon, David McGuigan and Michael Graham in the back row.
Malone and Quins clash at Gibson Park in the big Belfast derby.
The host are sixth three points adrift of their cross city rivals and will be looking revenge for the 36-3 defeat Quins inflicted on them at Deramore in the first league meeting.
John Creightton has been released by Ireland U20’s and starts at scrum half for Malone with Josh Pentland at out half.
Mark Gribben starts in the centre beside Johnny Burgess and Malone have a pacey back three of Chris Leathem, Michael Barker and Taylor Acheson.
In the pack former Scottish U20 Nial Shannon starts at blindside flanker but is likely to move to hooker in the second half.
Connor Joyce is unavailable and captain Glen Moore is injured so Neil Alcorn starts at No8 with Johnny Ogilby at openside.
Chris Taylor is unavailable in the front row so Lee Barlow and David Halliday prop with Darryl Maxwell starting at hooker.
Ulster lock Alan O’Connor has been released and is partnered in the second row by Corrie Tipping.
Quins are hopefully of having Michael Heaney released by Ulster and he’ll start at outhalf with Roger Kirkwood at scrum half.
Ryan Martin comes into the midfield to partner Mark Best.
In the pack Paul Greenaway starts at tight head prop with Paul Rea in the second, Ulster Raven Sean O’Connell makes the bench after a long injury.
Dungannon are a point above the relegation places and face a tough task as second placed UCD come to Stevenson Park.
With two sides going down Paddy Johns men are 14th with Bruff 15th and Ballymena bottom on nine points.
Gannon could have Ali Birch and Chris Cochrane available depending on how much game time they got for Ulster last night.
Glen Sinnamon and Mark Farquhar earn starts in the front row while hooker Paul Jackson retains his place from last week’s defeat.
Mark Jenkinson returns to the second row to partner Paul McCarroll, Mark Dunleavy switches to blindside flanker with Rowan Halsall and Timmy Smith due to start if Birch isn’t released.
Behind the pack Jake Finlay continues at scrum half with Gareth McGonigle at outhalf.
Stuart McCloskey and Paul Magee are in midfield, Sean Conway will start on the wing if Cochrane is not released with Darren Simpon on the other and Jaryd Bennett at full back.
Ballymena plight at the foot of the table is looking perilous, coach John Andrews left last week and they suffered a 66-5 defeat at Hinch, they host seventh placed Blackrock at Eaton Park.