The new SDLP leader Colum Eastwood said he was politically opposed to Mr Robinson, but wished him well.
He said they had often been “polar opposites” in recent years when it came to their political stances.
He said: “His early career was forged as a right leaning, hard-line unionist so it’s unsurprising that we don’t have much political common ground. But despite our disagreements, on a human level it’s clear to see that he has had a very difficult time personally and with his health.
“Politics here is often dominated by cults of personality and we’re all guilty of forgetting that beneath that, there are people with families and their own lives. I want to wish the First Minister all the best in the future and the best of health so that he can enjoy his retirement.”