Malone have two games to save their Division 1B status.
Jacque Benade’s side go into the penultimate weekend in ninth place - just a point ahead of basement club Corinthians and a point behind UL Bo’s.
Malone travel to second placed Garryowen who need a win to confirm promotion.
Elsewhere, Corinthians face Dublin University who have a slim chance of going up while Bo’s travel mid-table Buccaneers, the Connacht side had shipped 91 points in their last two outing.
Malone are boosted by the return of Ulster lock Alan O’Connor.
Hooker Paul Jackson and prop Bronson Ross are on the bench for Ulster tonight but will be released depending on game time.
Ulster Ravens back row Connor Joyce is also released.
A win at Deramore against Corinthians last time out guaranteed Belfast Harlequins Division 1B rugby next season.
Adam Larkin’s men finish their home campaign Galwegians who are already promoted.
Adam Larkin has a choice of whether to player prop Ricky Lutton or lock Neil McComb.
Frank Taggat and Michael Heaney are released while Sean Reidy and Rory Scholes could be available depending on game time for Ulster tonight.