Old Wesley’s win over UCC last week virtually guarantees the Donnybrook side’s promotion from Division 2A.
That leaves six clubs fighting for the other automatic promotion spot, Queen’s are fourth three points of second with Banbridge in seventh are a further three points adrift of the students.
Queen’s face a tricky away trip to Tipperary to face mid table Nenagh.
Bob Young is without his Ireland U20 quintet, while Ulster Ravens half back duo Connor Young and Sean O’Hagan are also missing.
Centre pairing Conor Shiels (ankle) and Stuart McIlwaine (shoulder) both face fitness tests while Connor McKee is unavailable.
Justin Rea returns to out half as Ali Wright is injured with Connor Spence at out half.
Eoin Devlin, a try scorer in the bonus point win over Dungannon, starts on the wing.
In the pack Norman Sinclair, Scott Finlay and Andrew Kerr are all vying for the starting spot at hooker.
Hugh Sloane and Nigel Simpson form the second row partnership with Stuart Hooks, Josh Atkinson and Ryan Clarke in the back row.
Banbridge welcome struggling Seapoint to Rifle Park, the Dublin side are a point of the bottom.