Seven days ago there were 382 Covid inpatients but that figure stood at 257 on Thursday afternoon.
The deaths occurred in the following local council areas: Antrim and Newtownabbey (one); Lisburn and Castlereagh (one) and Ards (one).
Two of the deceased were male and one was female.
One of the deceased was aged between 60 and 79 while the remaining two individuals were aged 80 or older.
The DoH also recorded 163 new infections in the last 24 hours.
It means the total number of individuals to test positive for Covid-19 over the last seven days and since the pandemic began is now 1,305 and 113,169 respectively.
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