Across the weekend, many former Irish League stars or Northern Ireland internationals will take to the pitch in one of the world’s most famous competitions.
Some of the biggest ties see Liverpool hosting Accrington Stanley at Anfield, Chelsea welcoming Morecambe to Stamford Bridge and Tamworth take on Premier League opposition in Tottenham Hotspur.
Here’s every local representative to watch out for over the weekend.
9. Trai Hume (Sunderland)
Trai Hume gained senior experience with Linfield and Ballymena United before earning a move to Sunderland and has even been linked with Premier League moves. His side face Stoke City in the FA Cup on Saturday. Photo: Jess Hornby/PA Wire
10. Daniel Ballard (Sunderland)
Daniel Ballard has developed into a crucial player for both Sunderland and Northern Ireland. The defender will likely line up alongside Trai Hume at the Stadium of Light. Photo: Ian Hodgson/PA Wire
11. Jordan Thompson (Stoke City)
Former Manchester United youngster Jordan Thompson has played 12 Championship matches for Stoke City this season but has spent a period on the sidelines. It's unclear if he will be back for Saturday's FA Cup clash with Sunderland. Photo: Nigel French/PA Wire
12. Conor Hazard (Plymouth Argyle)
Downpatrick native Conor Hazard has recently regained his Plymouth starting spot after recovering from injury and could be between the sticks against Premier League side Brentford on Saturday afternoon. Photo: Steven Paston/PA Wire