Across the weekend, many former Irish League stars or Northern Ireland internationals will take to the pitch in one of the world’s most famous competitions.
Some of the biggest ties see Liverpool hosting Accrington Stanley at Anfield, Chelsea welcoming Morecambe to Stamford Bridge and Tamworth take on Premier League opposition in Tottenham Hotspur.
Here’s every local representative to watch out for over the weekend.
13. Josh Magennis (Exeter City)
Northern Ireland striker Josh Magennis' Exeter City side host Oxford United on Saturday afternoon. He has scored three league goals in 23 appearances this season. Photo: Arthur Allison/Pacemaker Press
14. Ciaron Brown (Oxford United)
Ciaron Brown has been a consistent presence in Oxford United's defence in the Championship this season and could line out again on Saturday in the FA Cup against Josh Magennis' Exeter City. Photo: Bradley Collyer/PA Wire
15. Stephen Dooley (Harrogate Town)
Former Coleraine star Stephen Dooley, who was a Northern Ireland youth international, is set for a big day out at Elland Road when his Harrogate Town visit Leeds United. Photo: INPHO/PressEye.com/Jonathan Porter
16. Matty Lund (Salford City)
Matty Lund, who played three times for Northern Ireland, will hope to cause a massive FA Cup shock when his Salford City side visit Premier League giants Manchester City. Photo: Barrington Coombs/PA Wire