Rea requires two more victories to draw level with Foggy and has enjoyed plenty of success at the Italian circuit in the past, claiming doubles in 2014 and 2015.
The Kawasaki rider, who leads the championship by 30 points going into the fifth round, said: “It’s been good to be at home and recharge the batteries after our recent back to back races, and then a test in Brno.
“I’m feeling good ahead of the Imola weekend. It’s a track that has a fun and challenging layout. It’s also been a circuit where we have just lacked that last piece of the jigsaw in recent years so it would be great to try to improve on our most recent Imola form.
“It’s such a picturesque circuit and steeped in history – it’s impossible not to enjoy riding there, especially in front of the Italian fans for the first time in 2018. We will be targeting race wins, let’s see if we can do it!”
Jeremy McWilliams notches Bishopscourt double at Classic Bike Festival Ireland on Michael Dunlop's Team Classic Suzuki
Blackpool reject bid for Shayne Lavery amid Millwall speculation
Tributes to ‘Mr Belfast’ Jim Gillespie after former Belfast Giants owner passes away
FULL MEDAL TALLY for the four home nations in the Commonwealth Games: Northern Ireland comes in just behind South Africa and Malaysia
In Pictures: Team NI's Commonwealth Games medal winners
Race one is scheduled for 12:00 BST on Saturday, with the second race at the same time on Sunday.